Book review – Diagnostic Pathology: Pediatric Neoplasms, 3rd Edition
The 3rd edition of Diagnostic Pathology: Pediatric Neoplasms by Angelica R Putnam and Karen S Thompson continues to serve as a comprehensive reference for the diagnosis and management of paediatric neoplasms. As a part of the Diagnostic Pathology series, this edition offers a detailed update, reflecting the latest advances in paediatric oncology and pathology.
The book maintains the well-organised approach of previous editions, providing comprehensive descriptions, histological images and diagnostic criteria for a wide range of paediatric neoplasms. I found this user-friendly structure particularly appealing; I believe it is highly regarded by those familiar with the Diagnostic Pathology series.
The text encompasses most neoplastic conditions affecting children, from common tumours to rare malignancies. The inclusion of high-resolution histopathological images remains a cornerstone, facilitating visual recognition and comparison, which is further enhanced by the incorporation of diverse clinical, radiographic and gross images. There is an increased emphasis on the clinical aspects of paediatric tumours, including presentations, prognoses and therapeutic strategies. Notably, the expanded sections on molecular diagnostics and genetic underpinnings of paediatric neoplasms reflect the growing significance of personalised medicine.
Several significant enhancements and updates distinguish the third edition from its predecessor. Updated content includes newly recognised tumour entities and updated classifications aligned with the latest World Health Organization guidelines. There is an increased focus on molecular pathology and genetics, offering insights into the pathogenesis and targeted therapies for various paediatric neoplasms.
This 3rd edition features very high-quality images with more comprehensive image sets for each neoplasm, encompassing a broader spectrum of histopathological variations. The layout and organisation have been refined, enabling intuitive navigation and cross-referencing. Furthermore, the inclusion of additional tables and summary boxes condenses key diagnostic criteria, differential diagnoses and prognostic factors, making the text accessible to experts and junior pathologists alike. Compared with the previous 2 editions, there is stronger integration of clinical information with pathological findings, facilitating a holistic understanding of each neoplasm. Lastly, this edition introduces diagnostic algorithms and flowcharts to streamline the diagnostic process.
The text exhibits several notable strengths, some of which have been retained from previous editions but are still worth mentioning. The content is up to date with the latest advances in paediatric oncology, ensuring its relevance in contemporary practice. The authors acknowledge that the range of ancillary studies aiding diagnosis, prognostication and therapeutic information will continue to expand and evolve. As such, the accessible and portable eBook version included with each printed version of the text can be updated as information becomes available, maintaining the content’s currency. The inclusion of abundant high-quality images plays a crucial role in facilitating visual diagnosis and learning for pathologists. The integration of clinical, pathological and molecular information makes it a valuable resource for pathologists, oncologists and paediatricians.
Potential drawbacks of the text include its complexity and cost. The depth and complexity of information may be overwhelming for those new to the field; a foundational understanding of pathology and oncology is required. In addition, as with many specialised medical textbooks, the cost may be prohibitive for certain readers, especially students or practitioners in resource-constrained settings.
Overall, Diagnostic Pathology: Pediatric Neoplasms, 3rd Edition is a significant upgrade from its predecessor. It reflects the rapid advances in the field of paediatric pathology. The comprehensive coverage, high-quality images and practical integration of clinical and molecular data make it an indispensable resource for professionals dealing with paediatric tumours.
While it may be complex for novices, the user-friendly structure, bullet points and concise sentences enhance the text’s accessibility. The detailed and organised approach solidifies its position as a cornerstone reference for experienced practitioners. In my opinion, Putnam and Thompson have once again succeeded in delivering a comprehensive, current and highly valuable guide. I would recommend this beautifully presented textbook to any pathologist involved in the diagnosis of paediatric neoplasms.
Heather Keir
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